Research work · 2008

Variation of a Newcastle Disease Virus Hemagglutinin-Neuraminidase Linear Epitope

Sun-Hee Cho, Hyuk‐Joon Kwon, Taeeun Kim, Jae‐Hong Kim, Han-Sang Yoo, Sun-Joong Kim

Journal of Clinical Microbiology

Abstract

Fifty-six Newcastle disease virus strains collected from 2000 to 2006 could be grouped into subgenotype VIId. However, they displayed cumulative mutations in and around the linear epitope of hemagglutinin-neuraminidase (residues 345 to 353) with time. The antigenicities of the variants that became predominant in Korea differ from each other and from the wild type.

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DOI: 10.1128/jcm.00187-08