Research work · 2017

KMC 3: counting and manipulating k -mer statistics

Marek Kokot, Maciej Długosz, Sebastian Deorowicz

Bioinformatics

Abstract

SUMMARY: Counting all k -mers in a given dataset is a standard procedure in many bioinformatics applications. We introduce KMC3, a significant improvement of the former KMC2 algorithm together with KMC tools for manipulating k -mer databases. Usefulness of the tools is shown on a few real problems. AVAILABILITY AND IMPLEMENTATION: Program is freely available at http://sun.aei.polsl.pl/REFRESH/kmc . CONTACT: [email protected]. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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DOI: 10.1093/bioinformatics/btx304