Research work · 2002

Nanocapsule Technology: A Review

Patrick Couvreur, GILLIAN M. BARRATT, Elias Fattal, Christine Vauthier

Critical Reviews in Therapeutic Drug Carrier Systems

Abstract

Nanocapsules are submicroscopic colloidal drug carrier systems composed of an oily or an aqueous core surrounded by a thin polymer membrane. Two technologies can be used to obtain such nanocapsules: the interfacial polymerization of a monomer or the interfacial nanodeposition of a preformed polymer. This article is an extended review of these nanocapsule technologies and their applications for the treatment of various diseases (including cancer and infections).

DOI: 10.1615/critrevtherdrugcarriersyst.v19.i2.10