Research work · 2001
Integrons and Gene Cassettes in the Enterobacteriaceae
Peter A. White, Christopher J. McIver, William D. Rawlinson
Antimicrobial Agents and Chemotherapy
Abstract
Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase genes. PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the aminoglycosides and trimethoprim.