Research work · 2012
Organometallic chemistry
Organic Chemistry
Abstract
This chapter examines organometallic chemistry. It introduces the concepts of metal–ligand interaction, describes the most important reactions that can occur while ligands are bound to the metal, and demonstrates the power of organometallic chemistry in synthesis. The efficiency of transition metal-catalysed reactions means that they are routinely used in industrial synthesis. There is a simple guide to the stability of transition metal complexes: the 18-electron rule. If a complex satisfies the 18-electron rule it means that the metal at the centre of the complex has the noble gas configuration of 18-electrons in the valence shell, and the complex is likely to be stable. The chapter then considers that palladium is the most widely used metal in homogenous catalysis, before looking at the Heck reaction.